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- 22:31, 27 July 2025 Fmichael1 talk contribs created page Thalamopeduncular syndrome (Created page with " ## Definition & Etiology Thalamopeduncular syndrome (TPS) refers to a clinical presentation associated with lesions at the junction of the thalamus and cerebral peduncle. Primarily seen in pediatric patients (1-5% of brain tumors), it is often caused by low-grade gliomas (LGGs), such as pilocytic astrocytoma (PA) with KIAA1549-BRAF fusion or BRAF-V600E mutation. In adults, it may arise from vascular events like Artery of Percheron (AoP) occlusion leading to paramedian t...")